There is a lot of supposedly good information floating around these days if your algorithm is tuned to science instead of poltiics, but it's rough navigating the digital rivers of social media influencers.
Other than videos cutting off too soon, not explaining clearly the premise or conveying messages clearly, or otherwise failing to highlight keywords or relevance or include links to sources,
I hope we can begin to include (and read) more of the science,
Which is available, and for this particular topic Histotripsy, there are plenty of scholarly articles!
1 Google Scholar https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=histotripsy&btnG=
About 4,520 results
2 Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications https://www.tandfonline.com/doi/full/10.3109/02656736.2015.1007538 [2014] "In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within the body to locally affect the targeted site without damaging intervening tissues."
3 In vivo histotripsy brain treatment https://thejns.org/view/journals/j-neurosurg/131/4/article-p1331.xml [2018] "Histotripsy is an ultrasound-based treatment modality relying on the generation of targeted cavitation bubble clouds, which mechanically fractionate tissue."
4 Histotripsy: the first noninvasive, non-ionizing, non-thermal ablation technique based on ultrasound https://www.tandfonline.com/doi/full/10.1080/02656736.2021.1905189 [2021] "Histotripsy is the first noninvasive, non-ionizing, and non-thermal ablation technology guided by real-time imaging."
5 The histotripsy spectrum: differences and similarities in techniques and instrumentation https://www.tandfonline.com/doi/full/10.1080/02656736.2023.2233720 [2023] "Since its inception about two decades ago, histotripsy – a non-thermal mechanical tissue ablation technique – has evolved into a spectrum of methods, each with distinct potentiating physical mechanisms: intrinsic threshold histotripsy, shock-scattering histotripsy, hybrid histotripsy, and boiling histotripsy."
6 Histotripsy induces apoptosis and reduces hypoxia in a neuroblastoma xenograft model https://www.tandfonline.com/doi/full/10.1080/02656736.2023.2222941 [2021] "Histotripsy induced a 50% reduction in bioluminescence compared to untreated controls,with an absence of nuclei in the treatment core surrounded by a dense rim of TUNEL-positive cells."
7 Histotripsy: A Method for Mechanical Tissue Ablation with Ultrasound https://www.annualreviews.org/content/journals/10.1146/annurev-bioeng-073123-022334 [2024] "Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy tissue into subcellular debris using high-amplitude focused ultrasound pulses."
Can we please start providing the citations and the links to those sources in the comments of these videos? And ensure that your video is whole and complete to fit the format, so it doesn't cut off and leave the audience wondering why they wasted their time listening to incomplete content.
This is fascinating science! It deserves more than Shorts, Reels and TikToks give it.
"Histotripsy mechanism; using of high enough acoustic intensities with a short pulse duration, inertial cavitation will release a shockwave able to destroy cell membranes and even liquefying or annihilating targeted cells containing in tumor-tissues." [S]
"HistoSonics helped to pave the way for an expeditious approval when it secured Breakthrough Device Designation for Edison in 2021."
https://www.fusfoundation.org/posts/us-fda-clears-focused-ultrasound-to-noninvasively-treat-liver-tumors/
"HistoSonics is a privately held medical device company developing a non-invasive platform and proprietary sonic beam therapy utilizing the science of histotripsy, a novel mechanism of action that uses focused ultrasound to mechanically destroy and liquify unwanted tissue and tumors."
https://histosonics.com/news/fda-awards-histosonics-clearance-of-its-first-of-a-kind-edison-histotripsy-system-2/