Article name: Effect of Short-Term Supplementation of Potassium Chloride and Potassium Citrate on Blood Pressure in Hypertensives
This article was published in Hypertension in 2005. It is a randomized crossover trial that compares the effects of potassium chloride with potassium citrate.
At baseline, the blood pressure (BP) was 151±16/93±7 mm Hg with a 24-hour urinary potassium excretion of 81±24 mEq. During the randomized crossover part of the study, BP was 140±12/88±7 mm Hg with a 24-hour urinary potassium of 164±36 mEq on day 7 of potassium chloride administration, and BP was 138±12/88±6 mm Hg with a 24-hour urinary potassium of 160±33 mEq on day 7 of potassium citrate administration. These BPs were significantly lower compared with the one at baseline. There was no significant difference in BP between potassium chloride and potassium citrate.
The article shows that potassium potassium chloride and potassium citrate have a similar effect on blood pressure in patients with a diagnosis of hypertension.